Nodular Hyperplasia Mimicking Colon Cancer Liver Metastasis

Oxaliplatin-based chemotherapy protocols have improved survival in colorectal cancer as an adjuvant treatment. Nevertheless, sinusoidal obstruction syndrome (SOS) may occur during oxaliplatin therapy. Liver lesions related to sinusoidal obstruction syndrome can mimick liver metastasis. A 35-year-old female patient who has a history of right hemicolectomy due to colon adenocar-cinoma 10 years ago, received 9 cycles of 500 mg capecitabine and 100 mg oxaliplatin as an adjuvant chemotherapy. Suspicious nodules were diagnosed at the liver during magnetic resonance imaging (MRI) which was performed 10 years after right hemicolectomy. Surgical intervention was performed. Focal nodular hyperplasia was diagnosed for all the liver lesions after pathological evaluation. Patients with colorectal cancer who received oxaliplatin based chemotherapy with the new onset liver lesions should be examined carefully. Not only radiological evaluation but also core needle biopsy should be used for misdiagnosis and preventing overtreatment.