Inonu University Experience in Hepatitis B Recurrence After Liver Transplantation

Objectives: Hepatitis B virus (HBV), one of the biggest health problems of the world and our country, still constitutes the largest cause of liver failure and liver transplantation in the world. Here, we will introduce the HBV virus closely and share the health prob-lems of HBV in the world and in our country in the literature data.
Methods: İnönü University Liver Transplant Institute Patients who underwent liver transplantation due to any reason related to HBV were included in the study. Patients who underwent liver transplantation due to liver diseases caused by HBV in our institute between 2009 and 2023 were included in the study.. A total of 3679 patients underwent liver transplantation between 2002 and 2024. Of these patients, 1275 patients were operated on with the diagnosis of HBV. When 530 patients whose data were not avail-able and 49 patients who were retransplanted were excluded from the study, a total of 695 patients were included in the study. Results: Treatment is given in combination with antiviral and HBIG. It is available in centers where powerful antivirals are used alone. Although the approaches of the centers vary, patients who have had a liver transplant due to HBV definitely need postopera-tive medical treatment to prevent HBV recurrence.
Conclusion: Patients who have undergone liver transplantation due to HBV must have their Hbs-ag level checked when they are discharged from the hospital. Informing the patient about HBV recurrence and medical treatment provides a more meticulous medical treatment.