CARES, is a novel integrated screening and stepped collaborative care intervention developed for those with chronic illnesses and their family caregivers. This paper provides a history of collaborative care and the findings of Phase I-III trials in oncology and nephrology as well as transplantation. CARES is currently being testing in Hybrid Type I and II effectiveness-implementation cluster randomized controlled trials in oncology and nephrology, respectively.
Keywords: Stepped collaborative care, chronic illness, caregiving, oncology, nephrology, transplant