Varicella Zoster Fulminant Hepatitis in a Pediatric Patient with Leukemia: Recovery Without Liver Transplantation

Acute liver failure is a sudden and rapidly developing acute liver injury, with impaired metabolic-synthetic function of the liver, with or without encephalopathy that causes multi organ failure in a healthy person. Acute liver failure can develop due to many different reasons. In this report, we presented a child patient who received chemotherapy with the diagnosis of acute lymphoblastic leukemia and developed acute liver failure after Varicella-Zoster Virus infection.In this patient, liver transplantation could not be performed due to active viral infection, and she improved after acyclovir and supportive care with plasmapheresis. To the best of our knowledge, this is the only immunosuppressed child patient in the literature who improved from acute liver failure after Varicella-Zoster Virus infection without liver transplantation.